It Seems Like it is Everywhere Lately
Unless you have been living under a rock or are relatively new to the CBD/hemp scene, you have surely noticed the increased presence of CBG products. CBG can now be found as the dominant cannabinoid in many CBD concentrates and has even been isolated as the dominant cannabinoid in specific strains of hemp flower. This cannabinoid is said to have a wide array of impressive benefits, which we unfortunately cannot disclose for legal purposes. If you take the time to do a quick search of your own, you’ll surely find out why so many are giving CBG a try.
So What is it?
CBG, short for Cannabigerol is considered a minor cannabinoid. This is because in most strains of cannabis, it is found in concentrations of less than 1%. Cannabis plants produce cannabigerolic acid (CBGA), which is the precursor to the three main cannabinoids - tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), and cannabichromenic acid (CBCA).
Specific enzymes within the cannabis plant break down CBGA and convert it into one of the three main cannabinoids. The acid is exposed to heat or ultraviolet light which triggers their conversion into THC and CBD. In most strains, CBGA is immediately converted to either THCA or CBDA. Thus, more THC means less CBG & CBD (and vice versa) by nature of how these compounds are synthesized.
How Does it Work?
CBG, like other cannabinoids, works via the bodies endocannabinoid system. When cannabis is consumed, cannabinoids bind to receptor sites throughout our brain (receptors called CB-1) and body (CB-2).
Different cannabinoids have different effects depending on which receptors they bind to. Therefore, it is important to experiment with different strains and products with different cannabinoid profiles in order to find out what cannabinoids are most effective for you.
How is CBG Being Used?
CBG is available in many different products. CBG dabs are becoming more popular, and CBG flower is being sought after by many for the unique experience it provides compared to regular CBD hemp flower. And of course, CBG distillates, CBG isolates, CBG gummies, CBG tinctures and CBG capsules are hitting the market every day as well.
How Do CBG Concentrates Compare to CBD Concentrates?
Without discussing benefits (again, for legal purposes), CBG concentrates have a noticeably different effect than CBD concentrates. Although CBG is said to be non-psychoactive, it seems to have a much more noticeable cerebral presence when paired with a full spectrum of cannabinoids. This effect may be less or non-existent in a broad spectrum CBG concentrate such as CBG isolate, but this is something many have noticed with the full spectrum CBG concentrates.
CBG dabs also have a unique taste compared to CBD dabs. Quality CBG dabs processed from quality CBG flower will have a particular pepper flavor mixed with eucalyptus and some have said ginseng as well. It is a very pleasant and unique taste that can be a refreshing change from the common flavors present in CBD dominant concentrates.
What’s So Special About CBG?
What is special about CBG is that it has been found to act on very specific cannabinoid receptors in different areas of the body. Here are some of the findings regarding how CBG interacts with the human body.
- CBG binds to the many cannabinoid receptors in the eyes. It has displayed neuroprotectant properties, and it is considered a vasodilator(1).
- CBG has displayed anti-inflammatory properties throughout the body(2).
- In a 2015 study, CBG displayed effectiveness at protecting neurons in mice with Huntington’s disease, which is characterized by nerve cell degeneration in the brain(3).
- In a 2014 study, also with mice, CBG inhibited the growth of colorectal cancer cells and slowed colon cancer growth(4).
- Research has shown that CBG is an effective antibacterial agent, particularly against methicillin-resistant MSRA microbial strains resistant to several classes of drugs(5).
- In a 2016 study, CBG was found to be an effective appetite stimulant in rats(6).
- In a 2015 study that looked at the effects of five different cannabinoids on bladder contractions, CBG tested best at inhibiting muscle contractions(7).
These initial results have scientists excited about future research with CBG alone and in combination with other cannabinoids. Because CBG is non-psychotropic, it has a wide range of potential applications.
If you are interested in purchasing CBG concentrates or have any questions, feel free to contact us for more information!
(2): Gugliandolo, Agnese et al. “In Vitro Model of Neuroinflammation: Efficacy of Cannabigerol, a Non-Psychoactive Cannabinoid.” International journal of molecular sciences vol. 19,7, 2018. https://doi.org/10.3390/ijms19071992
(3): Valdeolivas, Sara et al. “Neuroprotective properties of cannabigerol in Huntington's disease: studies in R6/2 mice and 3-nitropropionate-lesioned mice.” Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics vol. 12,1, 2015, pp. 185-99. https://doi.org/10.1007/s13311-014-0304-z
(4): Borrelli, Francesca et al. “Colon carcinogenesis is inhibited by the TRPM8 antagonist cannabigerol, a Cannabis-derived non-psychotropic cannabinoid.” Carcinogenesis vol. 35,12, 2014, pp. 2787-97. https://doi.org/10.1093/carcin/bgu205
(5): Karas, John A et al. “The Antimicrobial Activity of Cannabinoids.” Antibiotics (Basel, Switzerland) vol. 9,7, 2020, pp. 406. https://dx.doi.org/10.3390%2Fantibiotics9070406
(6): Brierley, Daniel I et al. “Cannabigerol is a novel, well-tolerated appetite stimulant in pre-satiated rats.” Psychopharmacology vol. 233,19-20, 2016, pp. 3603-13. https://doi.org/10.1007/s00213-016-4397-4
(7): Pagano, Ester et al. “Effect of Non-psychotropic Plant-derived Cannabinoids on Bladder Contractility: Focus on Cannabigerol.” Natural product communications vol. 10,6, 2015, pp. 1009-12. https://pubmed.ncbi.nlm.nih.gov/26197538/
DISCLAIMER: All the above information is scientifically confirmable fact, not to be mis-interpreted as claim for any type of medical use or benefit. No medical claims, benefits, or suggestions have been made in this article.